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Browse the profiles below and you may just see if you can find your perfect partner. We have hundreds of members who have always been looking to meet someone just like you!AMGN) Kyprolis for priority review for the treatment of patients with relapsed multiple myeloma who have already gone through one prior treatment.Patients with relapsed or refractory multiple myeloma (RRMM) have limited treatment options and poor survival outcomes.The increasing adoption of lenalidomide-based therapy for frontline treatment of MM has resulted in a need for effective regimens for lenalidomide-refractory patients.
Subsequent dosing was per the approved schedule for daratumumab.Celgene’s strategy involves combining its knowledge and infrastructure in hematology, oncology, and inflammation with those of other prominent healthcare players.The launch of Johnson & Johnson’s Darzalex (daratumumab) has boosted the sales of Celgene’s Pomalyst.This phase 1b study evaluated daratumumab plus carfilzomib and dexamethasone (DKd) in patients with RRMM after 1-3 prior lines of therapy, including bortezomib and an immunomodulatory drug; lenalidomide-refractory patients were eligible.
Carfilzomib- and daratumumab-naïve patients (N = 85) received carfilzomib weekly on Days 1, 8, and 15 of each 28-day cycle (20 mg/m thereafter), and dexamethasone 40 mg/week.
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